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Regulatory T cells expressing the FoxP3 transcription factor have a profound and nonredundant role in several aspects of immunological tolerance. We will review here the specification of this lineage, its population dynamics, and the diversity of subphenotypes that correlate with their diverse roles in controlling inflammation in a variety of settings.
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ژورنال
عنوان ژورنال: Nature Reviews Urology
سال: 2018
ISSN: 1759-4812,1759-4820
DOI: 10.1038/s41585-018-0075-0